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1

Action of a cd24-specific deglycosylated ricin-a-chain immunotoxin in conventional and novel models of small-cell-lung-cancer xenograft

Uwe Zangemeister-Wittke, Hans-Peter Lehmann, Robert Waibel, Edward J. Wawrzynczak, Rolf A. Stahel

Journal:

International Journal of Cancer

Year:

1993

Language:

english

File:

PDF, 1.18 MB

english, 1993

2

Antisense oligonucleotides for cancer therapy—an overview

Stahel, Rolf A., Zangemeister-Wittke, Uwe

Journal:

Year:

2003

Language:

english

File:

PDF, 192 KB

english, 2003

3

Epithelial cell adhesion molecule-targeted drug delivery for cancer therapy

Simon, Manuel, Stefan, Nikolas, Plückthun, Andreas, Zangemeister-Wittke, Uwe

Journal:

Expert Opinion on Drug Delivery

Year:

2013

Language:

english

File:

PDF, 712 KB

english, 2013

4

Novel Prodrug-Like Fusion Toxin with Protease-Sensitive Bioorthogonal PEGylation for Tumor Targeting

Stefan, Nikolas, Zimmermann, Martina, Simon, Manuel, Zangemeister-Wittke, Uwe, Plückthun, Andreas

Journal:

Bioconjugate Chemistry

Year:

2014

Language:

english

File:

PDF, 2.58 MB

english, 2014

5

Potent anti-tumor effects of an anti-CD24 ricin A-chain immunotoxin in vitro and in a disseminated human Burkitt's lymphoma model in SCID mice

Roland Schnell, Ali A. Katouzi, Christoph Linnartz, Gisela Schoen, Silke Drillich, Martin-Leo Hansmann, Daniel Schiefer, Stefan Barth, Uwe Zangemeister-Wittke, Rolf A. Stahel, Volker Diehl, Andreas En

Journal:

International Journal of Cancer

Year:

1996

Language:

english

File:

PDF, 859 KB

english, 1996

6

Induction of apoptosis in lung-cancer cells following bcl-xL anti-sense treatment

Siân H. Leech, Robert A. Olie, Oliver Gautschi, A. Paula Simões-Wüst, Stefan Tschopp, Robert Häner, Jonathan Hall, Rolf A. Stahel, Uwe Zangemeister-Wittke

Journal:

International Journal of Cancer

Year:

2000

Language:

english

File:

PDF, 239 KB

english, 2000

7

bcl-xl antisense treatment induces apoptosis in breast carcinoma cells

A. Paula Simões-Wüst, Robert A. Olie, Oliver Gautschi, Siân H. Leech, Robert Häner, Jonathan Hall, Doriano Fabbro, Rolf A. Stahel, Uwe Zangemeister-Wittke

Journal:

International Journal of Cancer

Year:

2000

Language:

english

File:

PDF, 282 KB

english, 2000

8

Induction of apoptosis and chemosensitization of mesothelioma cells by Bcl-2 and Bcl-xL antisense treatment

Sally Hopkins-Donaldson, Richard Cathomas, A. Paula Simões-Wüst, Stefanie Kurtz, Larisa Belyanskya, Rolf A. Stahel, Uwe Zangemeister-Wittke

Journal:

International Journal of Cancer

Year:

2003

Language:

english

File:

PDF, 317 KB

english, 2003

9

Induction of apoptosis and chemosensitization of mesothelioma cells by Bcl-2 and Bcl-xL antisense treatment

S Hopkins-Donaldson, R Cathomas, AP Simões-Wüst, S Kurtz, L Belyanskya, RA Stahel, U Zangemeister-Wittke

Journal:

International Journal of Cancer

Year:

2003

Language:

english

File:

PDF, 28 KB

english, 2003

10

Cisplatin activates Akt in small cell lung cancer cells and attenuates apoptosis by survivin upregulation

Larisa L. Belyanskaya, Sally Hopkins-Donaldson, Stefanie Kurtz, Ana Paula Simões-Wüst, Shida Yousefi, Hans-Uwe Simon, Rolf Stahel, Uwe Zangemeister-Wittke

Journal:

International Journal of Cancer

Year:

2005

Language:

english

File:

PDF, 553 KB

english, 2005

11

Anti-tumor activity of a blocked ricin immunotoxin with specificity against the cluster-5A antigen associated with human small-cell lung cancer

Uwe Zangemeister-Wittke, Albert R. Collinson, Igor Fisch, Robert M. L. Jones, Robert Waibel, Hans-Peter Lehman, Rolf A. Stahel

Journal:

International Journal of Cancer

Year:

1993

Language:

english

File:

PDF, 853 KB

english, 1993

12

A comparison of 67Cu- and 131I-labelled forms of monoclonal antibodies SEN7 and SWA20 directed against small-cell lung cancer

Alan Smith, Uwe Zangemeister-Wittke, Robert Waibel, Thomas Schenker, P. August Schubiger, Rolf A. Stahel

Journal:

International Journal of Cancer

Year:

1994

Language:

english

File:

PDF, 608 KB

english, 1994

13

Antisense molecules for targeted cancer therapy

V. Wacheck, U. Zangemeister-Wittke

Journal:

Critical Reviews in Oncology/Hematology

Year:

2006

Language:

english

File:

PDF, 185 KB

english, 2006

14

Targeting the conversion of ceramide to sphingosine 1-phosphate as a novel strategy for cancer therapy

Andrea Huwiler, Uwe Zangemeister-Wittke

Journal:

Critical Reviews in Oncology/Hematology

Year:

2007

Language:

english

File:

PDF, 326 KB

english, 2007

15

Bcl-2 and bcl-xL Antisense Oligonucleotides Induce Apoptosis in Melanoma Cells of Different Clinical Stages

Olie, Robert A., Hafner, Christoph, Küttel, Renzo, Sigrist, Brigitte, Stahel, Rolf A., Zangemeister-Wittke, Uwe, Willers, Jörg, Dummer, Reinhard, Hall, Jonathan

Journal:

The Journal of Investigative Dermatology

Year:

2002

Language:

english

File:

PDF, 346 KB

english, 2002

16

An antisense oligonucleotide to cIAP-1 sensitizes prostate cancer cells to fas and TNFα mediated apoptosis

Kevin McEleny, Ronan Coffey, Colm Morrissey, Kate Williamson, Uwe Zangemeister-Wittke, John M. Fitzpatrick, R. William G. Watson

Journal:

Year:

2004

Language:

english

File:

PDF, 165 KB

english, 2004

17

Specific eradication of micrometastases by transfer of tumour-immune T cells from major-histocompatibility-complex congenic mice

Volker Schirrmacher, Paul von Hoegen, Andreas Griesbach, Hans-Jörg Schild, Uwe Zangemeister-Wittke

Journal:

Cancer Immunology, Immunotherapy

Year:

1991

Language:

english

File:

PDF, 1.26 MB

english, 1991

18

Transfer of long-lasting tumor immunity by immune T cells from MHC congenic mice: Migration, survival and tumor-protectivity of cytotoxic donor cells

Uwe Zangemeister-Wittke, Volker Schirrmacher

Journal:

Year:

1991

Language:

english

File:

PDF, 1.08 MB

english, 1991

19

Novel approaches to the treatment of small-cell lung cancer

U. Zangemeister-Wittke, R. A. Stahel

Journal:

Cellular and Molecular Life Sciences

Year:

1999

Language:

english

File:

PDF, 325 KB

english, 1999

20

Preparation and functional evaluation of new doxorubicin immunoconjugates containing an acid-sensitive linker on small-cell lung cancer cells

Barbara A. Froesch, Rolf A. Stahel, U. Zangemeister-Wittke

Journal:

Cancer Immunology, Immunotherapy

Year:

1996

Language:

english

File:

PDF, 686 KB

english, 1996

21

A novel immunotoxin recognising the epithelial glycoprotein-2 has potent antitumoural activity on chemotherapy-resistant lung cancer

Sandra Zimmermann, Winfried Wels, Barbara A. Froesch, Bernd Gerstmayer, Rolf A. Stahel, U. Zangemeister-Wittke

Journal:

Cancer Immunology, Immunotherapy

Year:

1997

Language:

english

File:

PDF, 163 KB

english, 1997

22

Krebsbehandlung mit Antisense-Molekülen

U. Zangemeister-Wittke

Journal:

Year:

2007

Language:

german

File:

PDF, 516 KB

german, 2007

23

ΔNp73 antisense activates PUMA and induces apoptosis in neuroblastoma cells

A.P. Simões-Wüst, B. Sigrist, L. Belyanskaya, S. Hopkins Donaldson, R.A. Stahel, U. Zangemeister-Wittke

Journal:

Journal of Neuro-Oncology

Year:

2005

Language:

english

File:

PDF, 250 KB

english, 2005

24

Induction of apoptosis and enhancement of chemosensitivity in human prostate cancer LNCaP cells using bispecific antisense oligonucleotide targeting Bcl-2 and Bcl-xL genes

KAZUKI YAMANAKA, PALMA ROCCHI, HIDEAKI MIYAKE, LADAN FAZLI, ALAN SO, UWE ZANGEMEISTER-WITTKE, MARTIN E. GLEAVE

Journal:

BJU International

Year:

2006

Language:

english

File:

PDF, 197 KB

english, 2006

25

Loss of sphingosine kinase-1 in carcinoma cells increases formation of reactive oxygen species and sensitivity to doxorubicin-induced DNA damage

Andrea Huwiler, Nataliya Kotelevets, Cuiyan Xin, Oleksandr Pastukhov, Josef Pfeilschifter, Uwe Zangemeister-Wittke

Journal:

British Journal of Pharmacology

Year:

2011

Language:

english

File:

PDF, 1.43 MB

english, 2011

26

Synergistic cytotoxicity of bcl-2 antisense oligodeoxynucleotides and etoposide, doxorubicin and cisplatin on small-cell lung cancer cell lines

Zangemeister-Wittke, U, Schenker, T, Luedke, GH, Stahel, RA

Journal:

British Journal of Cancer

Year:

1998

Language:

english

File:

PDF, 1.41 MB

english, 1998

27

Apoptosis - Regulation and clinical implications

Zangemeister-Wittke, U, Simon, H-U

Journal:

Cell Death & Differentiation

Year:

2001

Language:

english

File:

PDF, 121 KB

english, 2001

28

Silencing of death receptor and caspase-8 expression in small cell lung carcinoma cell lines and tumors by DNA methylation

Hopkins-Donaldson, S, Ziegler, A, Kurtz, S, Bigosch, C, Kandioler, D, Ludwig, C, Zangemeister-Wittke, U, Stahel, R

Journal:

Cell Death & Differentiation

Year:

2003

Language:

english

File:

PDF, 336 KB

english, 2003

29

Involvement of hTERT in apoptosis induced by interference with Bcl-2 expression and function

Del Bufalo, D, Rizzo, A, Trisciuoglio, D, Cardinali, G, Torrisi, M R, Zangemeister-Wittke, U, Zupi, G, Biroccio, A

Journal:

Cell Death & Differentiation

Year:

2005

Language:

english

File:

PDF, 482 KB

english, 2005

30

Treatment of melanoma cells with a bcl-2/bcl-xL antisense oligonucleotide induces antiangiogenic activity

Bufalo, Donatella Del, Trisciuoglio, Daniela, Scarsella, Marco, Zangemeister-Wittke, Uwe, Zupi, Gabriella

Journal:

Year:

2003

Language:

english

File:

PDF, 213 KB

english, 2003

31

Antisense to Apoptosis Inhibitors Facilitates Chemotherapy and TRAIL-Induced Death Signaling

UWE ZANGEMEISTER-WITTKE

Journal:

Annals of the New York Academy of Sciences

Year:

2003

File:

PDF, 2.17 MB

2003

32

Epithelial Glycoprotein-2 Expression is Subject to Regulatory Processes in Epithelial–mesenchymal Transitions During Metastases: an Investigation of Human Cancers Transplanted into Severe Combined Immunodeficient Mice

Milan Jojović, Elizabeth Adam, Uwe Zangemeister-Wittke, Udo Schumacher

Journal:

Journal of Molecular Histology

Year:

1998

Language:

english

File:

PDF, 171 KB

english, 1998

33

Bcl-2 Antisense Therapy for Cancer: The Art of Persuading Tumour Cells to Commit Suicide

U. Zangemeister-Wittke, A. Ziegler

Journal:

Year:

1998

File:

PDF, 1.08 MB

1998

34

Antisense Therapy: Current Status in Prostate Cancer and Other Malignancies

Martin Gleave, Hideake Miyake, Uwe Zangemeister-Wittke, Burkhard Jansen

Journal:

Cancer and Metastasis Reviews

Year:

2002

Language:

english

File:

PDF, 334 KB

english, 2002

35

Bcl-2/bcl-xL Bispecific Antisense Treatment Sensitizes Breast Carcinoma Cells to Doxorubicin, Paclitaxel and Cyclophosphamide

A. Paula Simões-Wüst, Thomas Schürpf, Jonathan Hall, Rolf A. Stahel, Uwe Zangemeister-Wittke

Journal:

Breast Cancer Research and Treatment

Year:

2002

Language:

english

File:

PDF, 165 KB

english, 2002

36

Analysis of ribosyl-modified, mixed backbone analogs of a bcl-2/bcl-xL antisense oligonucleotide

Robert A. Olie, Jonathan Hall, Francois Natt, Rolf A. Stahel, Uwe Zangemeister-Wittke

Journal:

Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression

Year:

2002

Language:

english

File:

PDF, 277 KB

english, 2002

37

Increased numbers of spontaneous SCLC metastasis in absence of NK cells after subcutaneous inoculation of different SCLC cell lines into pfp/rag2 double knock out mice

Stephan Sodeur, Sebastian Ullrich, Heike Gustke, Uwe Zangemeister-Wittke, Udo Schumacher

Journal:

Year:

2009

Language:

english

File:

PDF, 507 KB

english, 2009

38

DARPins Recognizing the Tumor-Associated Antigen EpCAM Selected by Phage and Ribosome Display and Engineered for Multivalency

Nikolas Stefan, Patricia Martin-Killias, Sascha Wyss-Stoeckle, Annemarie Honegger, Uwe Zangemeister-Wittke, Andreas Plückthun

Journal:

Journal of Molecular Biology

Year:

2011

Language:

english

File:

PDF, 1.05 MB

english, 2011

39

Circulating DNA: a new diagnostic gold mine?

Annemarie Ziegler, Uwe Zangemeister-Wittke, Rolf A Stahel

Journal:

Cancer Treatment Reviews

Year:

2002

Language:

english

File:

PDF, 182 KB

english, 2002

40

Antisense strategies for induction of tumor cell apoptosis

Uwe Zangemeister-Wittke, Rolf Stahel, Francois Natt, Jonathan Hall

Journal:

European Journal of Cancer

Year:

2001

Language:

english

File:

PDF, 121 KB

english, 2001

41

Antisense therapy for cancer—the time of truth

Burkhard Jansen, Uwe Zangemeister-Wittke

Journal:

The Lancet Oncology

Year:

2002

Language:

english

File:

PDF, 1.13 MB

english, 2002

42

Targeting tumor cell resistance to apoptosis induction with antisense oligonucleotides: progress and therapeutic potential

Robet.A. Olie, Uwe Zangemeister-Wittke

Journal:

Drug Resistance Updates

Year:

2001

Language:

english

File:

PDF, 171 KB

english, 2001

43

Targeting the Phosphoinositide 3-Kinase p110- Isoform Impairs Cell Proliferation, Survival, and Tumor Growth in Small Cell Lung Cancer

Wojtalla, A., Fischer, B., Kotelevets, N., Mauri, F. A., Sobek, J., Rehrauer, H., Wotzkow, C., Tschan, M. P., Seckl, M. J., Zangemeister-Wittke, U., Arcaro, A.

Journal:

Clinical Cancer Research

Year:

2013

Language:

english

File:

PDF, 1.30 MB

english, 2013

44

Antisense oligonucleotides targeting the expression of anti-apoptotic proteins in lung cancer cells

Stahel, R.A, Gautschi, O, Hall, J, Leech, S, Olie, R, Simoes-Wuest, P, Tschopp, S, Zangemeister-Wittke, U

Journal:

Year:

2000

Language:

english

File:

PDF, 221 KB

english, 2000

45

97 Cisplatin-induced apoptosis in malignant pleural mesothelioma cells involves p53 but not p14ARF

Hopkins-Donaldson, S., Marti, T.M., Belyanskaya, L.L., Simões-Wüst, A.P., Sigrist, B., Kurtz, S., Zangemeister-Wittke, U., Stahel, R.

Journal:

Year:

2006

Language:

english

File:

PDF, 43 KB

english, 2006

46

Cell surface antigens as therapeutic targets

Stahel, R., Pass, Maria, Zangemeister-Wittke, U.

Journal:

Year:

1997

Language:

english

File:

PDF, 131 KB

english, 1997

47

Molecular strategies for therapy of small cell lung cancer

Stahel, R, Zangemeister-Wittke, U

Journal:

Year:

1998

Language:

english

File:

PDF, 375 KB

english, 1998

48

Apoptosis regulation and drug resistance in malignant pleural mesothelioma

Zangemeister-Wittke, Uwe, Hopkins-Donaldson, Sally

Journal:

Year:

2005

Language:

english

File:

PDF, 128 KB

english, 2005

49

TRAIL-induced survival and proliferation of SCLC cells is mediated by ERK and dependent on TRAIL-R2/DR5 expression in the absence of caspase-8

Belyanskaya, Larisa L., Ziogas, Algirdas, Hopkins-Donaldson, Sally, Kurtz, Stefanie, Simon, Hans-Uwe, Stahel, Rolf, Zangemeister-Wittke, Uwe

Journal:

Year:

2008

Language:

english

File:

PDF, 965 KB

english, 2008

50

Neuronal differentiation by indomethacin and IBMX inhibits proliferation of small cell lung cancer cells in vitro

Lange, Annika, Gustke, Heike, Glassmeier, Günter, Heine, Markus, Zangemeister-Wittke, Uwe, Schwarz, Jürgen R., Schumacher, Udo, Lange, Tobias

Journal:

Year:

2011

Language:

english

File:

PDF, 1.56 MB

english, 2011

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